2-Chloropropane

Agrochemicals 2025-03-02

2-Chloropropane

Chemical Name: 2-Chloropropane
Synonyms: Isopropyl chloride; sec-Propyl chloride
CAS Number: 75-29-6
Molecular Formula: C₃H₇Cl (or (CH₃)₂CHCl)
Molecular Weight: 78.54 g/mol

Physical and Chemical Properties

  • Appearance: Colorless, volatile liquid
  • Odor: Sweet, chloroform-like
  • Melting Point: –117 °C (–179 °F)
  • Boiling Point: 35.7 °C (96.3 °F)
  • Density: 0.862 g/cm³ (at 20 °C)
  • Vapor Pressure: 400 mmHg (at 20 °C)
  • Refractive Index: 1.377 (at 20 °C)
  • Flash Point: –32 °C (–26 °F) (Highly flammable)
  • Solubility:
    • Slightly soluble in water (0.3 g/100 mL at 20 °C).
    • Miscible with ethanol, ether, and most organic solvents.

Chemical Properties

  • Reactivity:
    • Reacts with strong oxidizers (risk of fire/explosion).
    • Can decompose under heat to release hydrogen chloride (HCl).
  • Stability: Stable under normal conditions but highly volatile.

Hazard and Safety Information (GHS)

  • Hazard SymbolsF+ (Extremely flammable), Xi (Irritant)
  • Hazard Statements:
    • H225: Highly flammable liquid and vapor.
    • H315: Causes skin irritation.
    • H319: Causes serious eye irritation.
    • H335: May cause respiratory irritation.
  • Precautionary Measures:
    • P210: Keep away from heat/sparks/open flames.
    • P261: Avoid breathing vapor.
    • P303+P361+P353: IF ON SKIN (or hair): Remove contaminated clothing, rinse skin with water.

Storage & Handling

  • Store in a flammable liquids cabinet at temperatures <30 °C.
  • Use explosion-proof equipment and ground containers to prevent static sparks.
  • Handle in a well-ventilated area or under a fume hood.

Applications

  • Solvent for fats, oils, and resins.
  • Intermediate in organic synthesis (e.g., pharmaceuticals, agrochemicals).
  • Formerly used as an anesthetic (now obsolete due to toxicity).

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