2-(chloromethyl)-4-methylquinazoline

Name: 2-(Chloromethyl)-4-methylquinazoline. CAS Number: 109113-72-6. Molecular Formula: C10H9ClN2. Molecular Weight: 192.64486 g/mol. Melting Point: 61-63°C. Usage: Mainly used as an intermediate i...

Introduction

Name: 2-(Chloromethyl)-4-methylquinazoline.

CAS Number: 109113-72-6.

Molecular Formula: C10H9ClN2.

Molecular Weight: 192.64486 g/mol.

Melting Point: 61-63°C.

Usage: Mainly used as an intermediate in pharmaceutical synthesis.

 

Attribute Details
Chemical Name 2-(Chloromethyl)-4-methylquinazoline
CAS Number 109113-72-6
Molecular Formula C10H9ClN2
Molecular Weight 192.645 g/mol
Synonyms 2-Chloromethyl-4-methylchinazolin; Linagliptin Intermediate A; Linaint-I; 2-(3-HYDROXY-5-METHOXY-2-PROPYLPHENYL)ACETIC ACID (among others)
Appearance Crystalline-Powder, Light Yellow to Reddish Yellow
Melting Point 61 – 63 °C (or 61.0 to 65.0 °C in some sources)
Boiling Point 240.039 °C at 760 mmHg (or 240.0±32.0 °C in some predictions)
Flash Point 122.14 °C (or 122.1±10.7 °C in some sources)
Density Approximately 1.251 g/cm³ or 1.3±0.1 g/cm³ (may vary)
LogP 2.677 or 1.94 (depending on source)
Usage Primarily used as an intermediate in the synthesis of pharmaceuticals, specifically as an intermediate for Linagliptin. Also used for scientific research and experimental purposes.
Safety Information May cause severe skin burns and eye damage. Wear appropriate protective gear such as gloves, goggles, and a respiratory mask. In case of contact, seek medical attention immediately. Store in a cool, dark place, keeping the container tightly closed.
Stability Generally stable. Avoid contact with oxidizing agents and strong bases.

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