2-Chloromethyl-3-methyl-4-(2,2,2-trifluoro-ethoxy)-pyridine HCl CAS NO.:127337-60-4
Pharmaceutical Materials 2025-03-02
Catalog ID:811015
CAS NO.:127337-60-4
Purity:98%
MDL Number:MFCD00800224
Molecular Weight:276.0830
Melting point: 169~170°C
2-Chloromethyl-3-methyl-4-(2,2,2-trifluoro-ethoxy)-pyridine HCl is an organic compound with the CAS number 127337-60-4. This white powdery substance serves as an important intermediate in the synthesis of pharmaceuticals, notably in the production of the proton pump inhibitor lansoprazole. The compound features a chloromethyl group, a methyl group, and a trifluoroethoxy group substituted on a pyridine ring, contributing to its unique reactivity and properties.
| Property | Details |
|---|---|
| CAS Number | 127337-60-4 |
| Chemical Name | 2-Chloromethyl-3-methyl-4-(2,2,2-trifluoro-ethoxy)-pyridine HCl |
| Molecular Formula | C9H10Cl2F3NO |
| Molecular Weight | 276.08 g/mol |
| Appearance | White powder |
| Melting Point | 208-214°C |
| Solubility | Slightly soluble in DMSO, methanol, water |
| Storage Condition | 2-8°C |
| CAS Database | 127337-60-4 (CAS DataBase Reference) |
| EINECS Number | 2017-001-1 |
| Uses | Pharmaceutical intermediate, specifically for lansoprazole synthesis |
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