2-chloro-5-trifluoromethylpyridine

We are a manufacturer based in China, specializing in high-quality 2-chloro-5-trifluoromethylpyridine for industrial clients worldwide. Technical support and custom formulation available.

Category:Agrochemicals  |  Brand:MT

Factory Direct 7-30 Days Lead Time MOQ: 100KG Global Export

Introduction

Uses of p-Fluorotoluene

p-Fluorotoluene serves as a key intermediate in the synthesis of:

  • Herbicides:
    • Fluazifop-butyl
    • Haloxyfop-methyl
  • Pesticides:
    • Chlorfluazuron

Production Methods

  1. Chlorotrifluoromethylpyridine Route:
    • Step 1: Chlorination of 2-chloro-5-trichloromethylpyridine (derived from 3-methylpyridine).
    • Step 2: Fluorination to yield the final product.
  2. Alternative Routes:
    • From 3-methylpyridine: Direct fluorination using a catalyst.
    • From 2-chloro-5-methylpyridine:
      • Side-chain chlorination to 2-chloro-5-trichloromethylpyridine.
      • Fluorination with hydrogen fluoride (HF).

Storage & Safety Precautions

  • Storage Conditions:
    • Cool, ventilated warehouse.
    • Separation: Isolate from oxidizers and food-grade chemicals.
    • Container: Must be tightly sealed.
  • Hazard Mitigation:
    • Fire Safety:
      • Keep away from heat/flames.
      • Lightning protection and explosion-proof equipment required.
    • Static Control:
      • Grounded exhaust systems.
    • Operational Restrictions:
      • Prohibit spark-generating tools.
  • Emergency Preparedness:
    • Leak-handling equipment and absorbent materials on-site.

Disclaimer

The content provided is for industry professionals’ reference only. Accuracy is not guaranteed. Purchasers must comply with all legal requirements and possess valid qualifications.

 

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