Pharmaceutical Materials

CAS No.456-04-2

Name:

2-chloro-4′-fluoroacetophenone

Synonyms:

AKOS BBS-00004073

LABOTEST-BB LT00233195

2-CHLORO-4′-FLUOROACETOPHENONE

2′-CHLORO-4-FLUOROACETOPHENONE

α-chloro-4′-fluoroacetophenone

2-chloro-4′-fluoroacetophenone

2-Chloro-4′-fluoro acetophenone

ALPHA-CHLORO-4-FLUOROACETOPHENONE

omega-chloro-4-fluoroacetophenone

alpha.-Chloro-p-Fluoroacetophenone

.alpha.-Chloro-p-Fluoroacetophenone

2-Chloro-1-(4-fluorophenyl)ethanone

2-CHLORO-1-(4-FLUOROPHENYL)ETHANONE

2-Chloro-4′-Fluoroacetophenone 2-Chloro-1-(4-Fluorophenyl)ethanone

Reference Information:

Uses    2-chloro-4′-fluoroacetophenone is an intermediate used in the synthesis of various pharmaceutical compounds. It can be used as a new antibacterial and antifungal agent to synthesize clinfloxacin triazole hybrids.

Used as a pharmaceutical intermediate

 

Category	Details
Basic Information
Name	2-Chloro-4′-fluoroacetophenone
CAS Number	456-04-2
EINECS Number	207-256-4
Molecular Formula	C8H6ClFO
Molecular Weight	172.59 (approx.)
Synonyms & Aliases	α-Chloro-4′-fluoroacetophenone; α-Chloro-4-fluoroacetophenone; 2′-Chloro-4-fluoroacetophenone; 2-Chloro-1-(4-fluorophenyl)ethanone; omega-Chloro-4-fluoroacetophenone
Physical Properties
Appearance	Shallow yellow crystals or transparent to pale yellow liquid
Melting Point	47-50°C
Boiling Point	246.98°C
Density	1.264 g/cm³
Flash Point	103.17°C
Safety Information
Risk Phrases	R23/25: Toxic by inhalation and if swallowed; R34: Causes burns; R36/37/38: Irritating to eyes, respiratory system, and skin
Safety Phrases	S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; S28: After contact with skin, wash immediately with plenty of soap and water; S36/37/39: Wear suitable protective clothing, gloves, and eye/face protection; S45: In case of accident or if you feel unwell, seek medical attention immediately (show the label where possible)
Applications	Used as an intermediate in pharmaceuticals and organic synthesis, particularly in the synthesis of antibacterial and antifungal agents like triazole hybrids.

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