Pharmaceutical Materials

2-Chloro-3-methylthiophene

Pharmaceutical Materials 2025-03-02

CAS Number: 14345-97-2

Molecular Formula: C5H5ClS

Molecular Weight: 132.61 g/mol

Appearance: Transparent to yellow liquid

Boiling Point: 147-149°C

Density: 1.211 g/mL at 25°C

Usage: Used as an organic synthesis intermediate.

Aspect	Details
Name	2-Chloro-3-methylthiophene
CAS No.	3302-43-2
Molecular Formula	C₅H₅ClS
Molecular Weight	132.61 g/mol
Physical Properties	Appearance: Colorless to pale yellow liquid Boiling Point: 163-165 °C Melting Point: -50 °C (approximate) Density: 1.23 g/cm³ Solubility: Insoluble in water; soluble in organic solvents like ethanol, ether, and chloroform
Chemical Properties	Contains a chlorine atom and a methyl group on the thiophene ring, which confers reactivity in nucleophilic substitution and cross-coupling reactions. The thiophene ring imparts stability and unique electronic properties, making it valuable in organic synthesis.
Applications	Used as a building block in the synthesis of pharmaceuticals, such as antifungal and antiviral agents Employed in the preparation of agrochemicals and specialty chemicals Acts as an intermediate in the development of functional materials and polymers
Safety Information	Flammable; handle with proper ventilation and protective equipment Avoid contact with eyes, skin, and inhalation Store in a cool, dry place away from heat and open flames

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2-Chloro-3-methylthiophene

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