2-Chloro-3-cyanopyridine
Pharmaceutical Materials 2025-03-02
CAS Number: 6602-54-6
Molecular Formula: C6H3ClN2
Molecular Weight: 138.554 g/mol
Appearance: White to off-white crystalline solid
Usage: Widely used as an intermediate in organic synthesis and pharmaceutical chemicals, especially for the preparation of nevirapine and mirtazapine.
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| Attribute | Details |
|---|---|
| Chemical Name | 2-Chloro-3-cyanopyridine |
| Synonyms | 3-cyano-2-chloropyridine; 2-chloro-3-pyridinecarbonitrile; 2-Chloro-3-cyanopyridne |
| Molecular Formula | C6H3ClN2 |
| Molecular Weight | 138.55 g/mol |
| CAS Number | 6602-54-6 |
| Chemical Structure | A heterocyclic compound with a pyridine ring, where the 2-position is substituted with a chloro group (-Cl) and the 3-position with a cyano group (-CN). |
| Physical Properties | – (Specific physical parameters such as melting point, boiling point, density, etc., are not provided in the references but can be obtained through experimental determination.) |
| Chemical Properties | It is sensitive to oxidizing agents. The chloro group at the 2-position can undergo dechlorination functionalization reactions under the attack of strong nucleophiles. The cyano group at the 3-position can undergo reduction, hydrolysis, and condensation reactions with amino alcohols. |
| Applications | Widely used as an intermediate in organic synthesis and as a raw material in pharmaceutical chemistry. It can be used in the preparation of pharmaceutical molecules such as nevirapine. |
| Safety Information | Handle with care. Store in a cool, dry place, ensuring good ventilation or exhaust ventilation in the workplace. (Specific safety hazards and precautions should refer to relevant MSDS documents.) |
