Pharmaceutical Materials

CAS Number: 1003-09-4

Molecular Formula: C4H3BrS

Molecular Weight: 163.04 g/mol

Appearance: Colorless to slightly brownish liquid

Melting Point: -10 °C

Boiling Point: 149-151 °C

Density: 1.684 g/mL at 25 °C

Usage: Used as an intermediate in pharmaceutical and organic synthesis.

 

Aspect	Details
Name	2-Bromothiophene
CAS Number	615-37-0
Chemical Formula	C₄H₃BrS
Molecular Weight	163.04 g/mol
Physical Appearance	Colorless to pale yellow liquid
Melting Point	-39°C
Boiling Point	161-163°C
Density	1.61 g/cm³ at 20°C
Reactivity	Actively participates in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi). Susceptible to nucleophilic substitution.
Solubility	Insoluble in water; soluble in organic solvents (e.g., ethanol, ether, chloroform).
Applications	– Organic Synthesis: Key intermediate in the preparation of thiophene-based polymers, pharmaceuticals, and agrochemicals.
	– Materials Science: Used to functionalize conductive polymers for OLEDs, organic solar cells, and molecular electronics.
Safety Information	– Hazards: Toxic if ingested; causes skin and eye irritation.
	– Handling: Use PPE (gloves, goggles) in a well-ventilated area.
Storage Conditions	Store in a cool, dry, and tightly sealed container away from light and heat.

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