2-Bromophenol

Chemical Additives 2025-03-18

2-Bromophenol

Chemical Formula: C₆H₅BrO
Structure: Halogenated phenol with:

  • A ​hydroxyl group (-OH) and a ​bromine atom (-Br) at the ​2-position (ortho) on a benzene ring.
  • Combines properties of ​phenols and ​aryl halides.

Physical Properties

  • Appearance: Clear, colorless to pale yellow liquid.
  • Odor: Characteristic phenolic odor.
  • Reactivity:
    • Moisture-sensitive: Reacts under humid conditions.
    • Participates in ​electrophilic substitution and coupling reactions.

Applications

  1. Organic Synthesis:
    • Reagent for introducing ​2-bromophenyl groups into molecules.
    • Production of ​pharmaceuticals, agrochemicals, and fine chemicals.
  2. Biomolecule Modification:
    • Functionalizes peptides and biomolecules.
  3. Industrial Chemistry:
    • Intermediate for ​dyes and ​polymers.

Safety Considerations ⚠️

  • Health Hazards:
    • Causes ​severe irritation to skin, eyes, and respiratory system.
  • Handling:
    • Use ​PPE (gloves, goggles, respirator) and work in a ​fume hood.
  • Storage:
    • Store in a ​cool, dry place away from ​moisture and incompatible materials (e.g., strong oxidizers).

Summary:
2-Bromophenol’s ​dual phenolic and halogenated properties make it versatile in synthesizing complex molecules and industrial products. Strict ​safety protocols are critical due to its reactivity and irritant nature.