2-Bromophenol
Chemical Additives 2025-03-18
2-Bromophenol
Chemical Formula: C₆H₅BrO
Structure: Halogenated phenol with:
- A hydroxyl group (-OH) and a bromine atom (-Br) at the 2-position (ortho) on a benzene ring.
- Combines properties of phenols and aryl halides.
Physical Properties
- Appearance: Clear, colorless to pale yellow liquid.
- Odor: Characteristic phenolic odor.
- Reactivity:
- Moisture-sensitive: Reacts under humid conditions.
- Participates in electrophilic substitution and coupling reactions.
Applications
- Organic Synthesis:
- Reagent for introducing 2-bromophenyl groups into molecules.
- Production of pharmaceuticals, agrochemicals, and fine chemicals.
- Biomolecule Modification:
- Functionalizes peptides and biomolecules.
- Industrial Chemistry:
- Intermediate for dyes and polymers.
Safety Considerations ⚠️
- Health Hazards:
- Causes severe irritation to skin, eyes, and respiratory system.
- Handling:
- Use PPE (gloves, goggles, respirator) and work in a fume hood.
- Storage:
- Store in a cool, dry place away from moisture and incompatible materials (e.g., strong oxidizers).
Summary:
2-Bromophenol’s dual phenolic and halogenated properties make it versatile in synthesizing complex molecules and industrial products. Strict safety protocols are critical due to its reactivity and irritant nature.


