2-bromoiodobenzene

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Introduction

Introduction

2-Bromoiodobenzene, also known as 1-bromo-2-iodobenzene, is a versatile chemical compound with a wide range of applications in organic synthesis, material science, and the pharmaceutical industry. This compound has the CAS number 583-55-1. Below is a detailed overview of this compound, presented in a table format for clarity.

Aspect Details
CAS Number 583-55-1
Molecular Formula C6H4BrI
Molecular Weight 282.9044 g/mol
Boiling Point 120-121°C (15 mmHg)
Density 2.203 g/mL at 25°C
Melting Point 9-10°C
Appearance Pale yellow to red liquid
Solubility Slightly soluble in ethanol, ether, and benzene, insoluble in water
Storage Conditions Store in a sealed container at room temperature, protected from light
Applications Organic synthesis intermediate, pesticide fungicide raw material, industrial disinfectant, LCD material, pharmaceutical intermediate
Safety Information Irritant. Safety labels: S37/39-S26. Danger labels: R36/37/38.
Suppliers Multiple suppliers available, offering various package sizes and prices

Chemical Properties

2-Bromoiodobenzene has a molecular formula of C6H4BrI and a molecular weight of 282.9044 g/mol. Its boiling point is 120-121°C at 15 mmHg, and its density is 2.203 g/mL at 25°C. The compound has a melting point of 9-10°C and appears as a pale yellow to red liquid. It is slightly soluble in ethanol, ether, and benzene, but insoluble in water. It should be stored in a sealed container at room temperature, protected from light.

Applications

This compound has multiple applications across different industries. It is used as an organic synthesis intermediate, particularly in the synthesis of other organic compounds. Additionally, it serves as a pesticide fungicide raw material, indicating its utility in pesticide production. It is also used as an industrial disinfectant, highlighting its significance in industrial cleaning processes. Furthermore, it is used as a liquid crystal display (LCD) material, suggesting its importance in the production of LCDs. It is also used as a pharmaceutical intermediate, indicating its role in drug synthesis.

Synthesis

2-Bromoiodobenzene can be synthesized through several methods. One common method is the diazotization reaction, where aniline is treated with sodium nitrite and hydrochloric acid to form a diazonium salt, which is then reacted with potassium iodide to yield iodobenzene. However, for 2-bromoiodobenzene, a specific synthesis route involves the use of o-dibromobenzene as a starting material, which is then reacted with n-butyl lithium at low temperatures to produce the desired compound.

Safety Information

2-Bromoiodobenzene is classified as an irritant. It is recommended to wear appropriate protective gear, such as gloves and goggles, to avoid contact. In case of contact, the affected area should be rinsed immediately with plenty of water, and medical attention should be sought. The compound should be stored in a sealed container at room temperature, protected from light, to ensure stability and prevent decomposition.

Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

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