2-Bromoethyl ethyl ether

Chemical Additives 2025-03-18

2-Bromoethyl Ethyl Ether

Chemical Formula: C₄H₉BrO
Structure: Halogenated ether with:

  • An ​ethyl group (-CH₂CH₃) and a ​2-bromoethyl group (-CH₂CH₂Br) bonded via an oxygen atom.

Physical Properties

  • Appearance: Clear, colorless to pale yellow liquid.
  • Odor: Mild.
  • Reactivity:
    • Moisture-sensitive: Reacts with water or humidity.
    • Highly reactive in nucleophilic substitution reactions.

Applications

  1. Organic Synthesis:
    • Reagent for introducing ​2-bromoethyl groups into target molecules.
    • Used in synthesizing ​pharmaceuticals, agrochemicals, and fine chemicals.
  2. Biomolecule Modification:
    • Functionalizes peptides and other biomolecules via alkylation.

Safety Considerations ⚠️

  • Health Hazards:
    • Causes ​severe irritation to skin, eyes, and respiratory system.
  • Handling:
    • Use ​PPE (gloves, goggles, lab coat) and work in a ​fume hood.
  • Storage:
    • Store in a ​cool, dry, airtight container away from ​moisture and incompatible substances (e.g., bases, strong oxidizers).

Summary:
2-Bromoethyl ethyl ether’s ​reactivity and ​halogenated ether structure make it valuable in organic synthesis and biomolecule engineering. Strict ​safety protocols are critical due to its irritant properties and moisture sensitivity.