2-Bromoethanol
Chemical Additives 2025-03-18
2-Bromoethanol
Chemical Formula: C₂H₅BrO
Structure: Halogenated alcohol with a two-carbon chain, featuring:
- A hydroxyl group (-OH) at one end.
- A bromine atom (-Br) at the other end.
- Combines properties of alcohols and alkyl halides.
Physical Properties
- Appearance: Clear, colorless to pale yellow liquid.
- Odor: Mild.
- Reactivity:
- Moisture-sensitive: Reacts with water.
- Bifunctional reactivity (OH and Br groups).
Applications
- Organic Synthesis:
- Reagent for introducing 2-bromoethyl groups into molecules.
- Synthesis of pharmaceuticals, agrochemicals, and fine chemicals.
- Biomolecule Modification:
- Functionalizes peptides and biomolecules via alkylation.
- Industrial Chemistry:
- Production of polymers and surfactants.
Safety Considerations ⚠️
- Health Hazards:
- Causes severe irritation to skin, eyes, and respiratory system.
- Handling:
- Use PPE (gloves, goggles, lab coat) and work in a fume hood.
- Storage:
- Store in a cool, dry, airtight container away from moisture and incompatible substances (e.g., strong bases, oxidizers).
Summary:
2-Bromoethanol’s dual functional groups enable versatile use in organic synthesis and biomolecule engineering. Its reactivity and bifunctional nature drive applications in drug development and industrial chemistry, but strict safety measures are essential due to its irritant properties and moisture sensitivity.


