Introduction
2-Bromoacetophenone Technical Specification
| Category |
Specifications |
| Chemical Name |
2-Bromoacetophenone |
| Synonyms |
Phenacyl bromide; α-Bromoacetophenone |
| CAS Number |
70-11-1 |
| Molecular Formula |
C₈H₇BrO |
| Molecular Weight |
199.05 g/mol |
| Appearance |
White to pale yellow crystalline solid |
| Melting Point |
48-51°C |
| Boiling Point |
135°C (15 mmHg) |
| Density |
1.647 g/cm³ (20°C) |
| Solubility |
Soluble in ethanol, ether; insoluble in water |
Chemical Properties
| Property |
Characteristics |
| Reactivity |
Strong lachrymator; alkylating agent |
| Stability |
Sensitive to light and moisture |
| Decomposition |
Releases HBr when heated |
| Characteristic Reactions |
Forms acetophenone derivatives via substitution |
Synthesis Methods
| Method |
Description |
| Bromination |
Direct bromination of acetophenone |
| Oxidation |
From styrene derivatives |
Applications
| Industry |
Use |
| Organic Synthesis |
Precursor for pharmaceuticals |
| Chemical Research |
Building block for heterocyclic compounds |
| Specialty Chemicals |
Intermediate for fragrances and dyes |
Safety & Handling
| Parameter |
Value/Requirement |
| OSHA PEL |
Not established |
| LD50 (oral, rat) |
150 mg/kg (estimated) |
| Skin/Eye Effects |
Severe irritant |
| Storage Conditions |
Cool, dry, dark place in airtight container |
| Personal Protection |
Gloves, goggles, respirator required |
Regulatory Status
| Regulation |
Status |
| Controlled Substances |
Restricted in some jurisdictions |
| EPA Classification |
Not listed as priority pollutant |
| EU REACH |
Registered substance |
Note: This compound is classified as a lachrymator (tear gas agent) and should be handled with extreme caution in well-ventilated areas using proper personal protective equipment. Its use is strictly regulated in many countries.
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