2-Bromo-3-methylthiophene

We are a manufacturer based in China, specializing in high-quality 2-Bromo-3-methylthiophene for industrial clients worldwide. Technical support and custom formulation available.

Category：Pharmaceutical Materials  |  Brand：MT

Factory Direct 7-30 Days Lead Time MOQ: 100KG Global Export

Introduction

CAS Number: 14282-76-9

Molecular Formula: C5H5BrS

Molecular Weight: 177.06 g/mol

Appearance: Colorless to pale yellow liquid

Boiling Point: 173-177.3°C

Density: 1.572-1.6±0.1 g/mL or g/cm3

Usage: Used as an intermediate in pharmaceutical and material science applications.

 

Aspect Details
Name 2-Bromo-3-methylthiophene
Common Synonyms 3-Methyl-2-bromothiophene, 2-Bromothiophen-3-methyl
CAS No. 5295-99-8
Molecular Formula C₅H₅BrS
Molecular Weight 177.06 g/mol
Physical Properties
  • Appearance: Colorless to pale yellow liquid
  • Boiling Point: 162-164 °C
  • Melting Point: -52 °C
  • Solubility: Insoluble in water; soluble in organic solvents (e.g., ethanol, ether)
  • Density: 1.55 g/cm³
Chemical Properties
  • Contains a bromine atom and a methyl group (-CH₃) on a thiophene ring (five-membered heterocycle with sulfur)
  • Exhibits electrophilic substitution reactivity due to the electron-rich nature of the thiophene ring
  • Undergoes nucleophilic substitution at the bromine position under suitable conditions
  • Stable under normal conditions but may react with strong nucleophiles or bases
Applications
  • Used as an intermediate in pharmaceutical synthesis (e.g., antiviral and antifungal agents)
  • Employed in agrochemicals as a building block for herbicides and pesticides
  • Utilized in organic synthesis for the preparation of polymers and specialty chemicals
Safety Information
  • GHS Hazards: H302 (harmful if swallowed), H315 (causes skin irritation), H226 (flammable liquid and vapor)
  • Precautionary Measures: Avoid inhalation and contact with eyes; use PPE
  • Storage: Keep in a tightly sealed container in a cool, well-ventilated area

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