Pharmaceutical Materials

CAS Number: 14282-76-9

Molecular Formula: C5H5BrS

Molecular Weight: 177.06 g/mol

Appearance: Colorless to pale yellow liquid

Boiling Point: 173-177.3°C

Density: 1.572-1.6±0.1 g/mL or g/cm3

Usage: Used as an intermediate in pharmaceutical and material science applications.

 

Aspect	Details
Name	2-Bromo-3-methylthiophene
Common Synonyms	3-Methyl-2-bromothiophene, 2-Bromothiophen-3-methyl
CAS No.	5295-99-8
Molecular Formula	C₅H₅BrS
Molecular Weight	177.06 g/mol
Physical Properties	Appearance: Colorless to pale yellow liquid Boiling Point: 162-164 °C Melting Point: -52 °C Solubility: Insoluble in water; soluble in organic solvents (e.g., ethanol, ether) Density: 1.55 g/cm³
Chemical Properties	Contains a bromine atom and a methyl group (-CH₃) on a thiophene ring (five-membered heterocycle with sulfur) Exhibits electrophilic substitution reactivity due to the electron-rich nature of the thiophene ring Undergoes nucleophilic substitution at the bromine position under suitable conditions Stable under normal conditions but may react with strong nucleophiles or bases
Applications	Used as an intermediate in pharmaceutical synthesis (e.g., antiviral and antifungal agents) Employed in agrochemicals as a building block for herbicides and pesticides Utilized in organic synthesis for the preparation of polymers and specialty chemicals
Safety Information	GHS Hazards: H302 (harmful if swallowed), H315 (causes skin irritation), H226 (flammable liquid and vapor) Precautionary Measures: Avoid inhalation and contact with eyes; use PPE Storage: Keep in a tightly sealed container in a cool, well-ventilated area

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