2-Amino-4-phenylbutane
Pharmaceutical Materials 2025-03-02
CAS Number: 22374-89-6
Molecular Formula: C10H15N
Molecular Weight: 149.23 g/mol
Appearance: Clear colorless liquid
Melting Point: -50°C
Boiling Point: 228-232°C
Usage: Used as an intermediate in chemical synthesis.
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| Attribute | Details |
|---|---|
| Name | 2-Amino-4-phenylbutane |
| Other Names | 1-Methyl-3-phenylpropan-2-amine; 1-Methyl-3-phenylpropylamine; 4-Phenyl-2-butanamine; α-Methylbenzenepropanamine |
| CAS Number | 22374-89-6 |
| Molecular Formula | C10H15N |
| Molecular Weight | 149.24 g/mol |
| Appearance | Colorless transparent liquid at room temperature |
| Physical Properties | Density: 0.92-0.936 g/mL; Melting Point: -50°C; Boiling Point: 220-221.5°C; Refractive Index: 1.5126-1.5146; Flash Point: 97.8-112°C; Soluble in chloroform and ethyl acetate, slightly soluble in water |
| Chemical Properties | Basic in nature, can form salts with acids such as hydrochloride and sulfate. Reacts with oxidizing agents like hydrogen peroxide and potassium permanganate. The amino group can undergo acylation, azidation, and other reactions. |
| Applications | Used as an intermediate in organic synthesis and pharmaceutical chemistry, particularly for the synthesis of drug molecules and the structural modification of biologically active molecules. It is a key intermediate in the synthesis of cardiovascular drugs like lidocaine. |
| Toxicological Properties | As a derivative of amphetamine, it may affect the release and reuptake of neurotransmitters, leading to central nervous system stimulation and euphoria. Long-term use may result in cognitive decline and addiction. |
| Safety Information | Handle with care, avoiding skin and eye contact. Store in a cool, dry place. In case of contact, rinse immediately with plenty of water and seek medical advice if necessary. Follow relevant safety regulations and guidelines during use. |
