2-Amino-4-chlorophenol
Pharmaceutical Materials 2025-03-02
CAS Number: 95-85-2
Molecular Formula: C6H6ClNO
Molecular Weight: 143.571
Appearance: Light brown crystals
Melting Point: 136-141°C
Boiling Point: 276.8°C at 760 mmHg
Flash Point: 121.2°C
Usage: Intermediate for dyes and organic synthesis.
| Attribute | Description |
|---|---|
| Name | 2-Amino-4-chlorophenol |
| CAS Number | 95-57-8 |
| Chemical Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Synonyms | 4-Chloro-2-hydroxyaniline, 2-Amino-4-chlorophenol (ortho), Orthochlorophenylenediamine monophenol, 4-Chloro-o-aminophenol |
| Chemical Structure | <img src=”https://example.com/2-amino-4-chlorophenol-structure” /> (Note: Replace with an actual image link) |
| Physical State | White to pale yellow crystalline powder |
| Melting Point | 158-161°C |
| Solubility | Slightly soluble in water; soluble in alcohol, ether, and benzene |
| pH | In aqueous solution, it can exist in both phenolic (weak acid) and amino (weak base) forms, affecting its pH behavior |
| Chemical Properties | Forms salts with acids and bases; reacts with diazonium salts in aromatic substitution reactions; undergoes electrophilic aromatic substitution reactions at the ring |
| Applications | Used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals; also used in the preparation of azo dyes and as a laboratory reagent |
| Production Method | Can be produced by the reduction of 4-chloro-2-nitrophenol or by the chlorination of 2-aminophenol followed by hydrolysis |
| Safety Hazards | May cause skin and eye irritation; harmful if swallowed or inhaled; may be toxic to aquatic organisms; handle with appropriate safety measures |
| Storage Conditions | Store in a cool, dry place, away from heat, sparks, and open flames; keep container tightly closed and protected from light |
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