2-Amino-4-chlorobenzonitrile

We are a manufacturer based in China, specializing in high-quality 2-Amino-4-chlorobenzonitrile for industrial clients worldwide. Technical support and custom formulation available.

Category:Pharmaceutical Materials  |  Brand:MT

Factory Direct 7-30 Days Lead Time MOQ: 100KG Global Export

Introduction

CAS Number: 38487-86-4

Molecular Formula: C7H5ClN2

Molecular Weight: 152.58 g/mol

Appearance: White or off-white powder

Melting Point: 157-162°C

Usage: Used as an organic synthesis intermediate.

 

Aspect Details
Name 2-Amino-4-chlorobenzonitrile
Common Synonyms 4-Chloro-2-aminobenzonitrile
CAS No. 55300-71-0
Molecular Formula C₇H₅ClN₂
Molecular Weight 152.58 g/mol
Physical Properties
  • Appearance: White to off-white crystalline solid
  • Melting Point: 118-120 °C
  • Solubility: Slightly soluble in water; soluble in organic solvents like ethanol, DMF, and DMSO
  • Density: Approximately 1.3 g/cm³ (estimated based on structure)
Chemical Properties Contains an amino group (-NH₂) and a nitrile group (-CN) on a chlorinated benzene ring. The amino group provides basicity and nucleophilicity, while the nitrile group can undergo hydrolysis or reduction reactions. The chlorine atom enhances reactivity in nucleophilic aromatic substitution.
Applications
  • Used as an intermediate in the synthesis of pharmaceuticals, including antivirals and anticancer agents
  • Employed in agrochemicals and specialty chemicals production
  • Acts as a building block for dyes and pigments
Safety Information
  • Handle with appropriate personal protective equipment to avoid skin and eye contact
  • Store in a cool, dry, and well-ventilated area

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