2-Amino-3-picoline
Pharmaceutical Materials 2025-03-02
CAS Number: 1603-40-3
Molecular Formula: C6H8N2
Molecular Weight: 108.14 g/mol
Appearance: Colorless to yellow liquid or crystalline solid
Melting Point: 29-31°C
Boiling Point: 220.9°C
Usage: Important organic intermediate in pharmaceutical and synthetic chemistry.
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| Attribute | Details |
|---|---|
| Chemical Name | 2-Amino-3-picoline |
| Other Names | 2-Amino-3-methylpyridine; 3-Methylpyridin-2-amine; 2-Amino-β-picoline; etc. |
| CAS Number | 1603-40-3 |
| Molecular Formula | C6H8N2 |
| Molecular Weight | 108.14 g/mol |
| Appearance | Yellow crystalline solid or colorless to light yellow liquid |
| Melting Point | 29-34 °C (literature values may vary slightly) |
| Boiling Point | 220.9-222 °C at 760 mmHg |
| Density | Approximately 1.1 g/cm³ or 1.068-1.073 g/cm³ (values may vary depending on source and temperature) |
| Solubility | Soluble in water and many organic solvents |
| Chemical Properties | Aromatic heterocyclic compound with an amino group and a methyl group attached to the pyridine ring; reacts with various reagents to form derivatives |
| Applications | Used as an intermediate in the synthesis of pharmaceuticals, pesticides, and other chemicals; also used in the preparation of dyes, surfactants, and other products |
| Synthesis Method | Can be synthesized through various chemical reactions, such as the hydrolysis of cyanides or the amination of halogenated pyridines |
| Safety Information | May cause skin and eye irritation; harmful if swallowed or inhaled; may have long-term health effects; wear appropriate protective equipment when handling; refer to the MSDS for detailed safety information and appropriate disposal methods |
