2-Amino-3-Bromobenzoic Acid

Pharmaceutical Materials 2025-03-02

CAS Number: 20776-51-6

Molecular Formula: C7H6BrNO2

Molecular Weight: 216.032 g/mol

Appearance: White solid

Usage: It is primarily used as an important pharmaceutical intermediate.

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Attribute Details
Chemical Name 2-Amino-3-Bromobenzoic Acid
Synonyms 3-Bromo-2-aminobenzoic acid
CAS Number 20776-51-6
Molecular Formula C7H6BrNO2
Molecular Weight 215.02 g/mol (or 216.03 g/mol, depending on source)
Appearance White to pale yellow solid
Melting Point 173-178 °C (varies slightly depending on source)
Boiling Point 343.5 °C at 760 mmHg
Density 1.793 g/cm³ or 1.8±0.1 g/cm³ (varies slightly depending on source)
Flash Point 161.5 °C
Solubility Soluble in organic solvents, slightly soluble in water
Stability Stable under normal conditions; incompatible with oxidizing agents and strong bases
Uses Important intermediate in pharmaceutical synthesis; used as an industrial raw material
Production Method Prepared by adding hydrogen peroxide dropwise to 7-bromoindigo, followed by neutralization with sodium hydroxide, adjusting the pH to 4 with hydrochloric acid, and precipitating the product as a white solid
Safety Instructions Handle with caution; avoid contact with skin, eyes, and inhalation of vapors; wear appropriate protective clothing and gloves; store in a cool, dry place away from incompatible substances; refer to the MSDS for detailed safety information