2-Amino-3-Bromobenzoic Acid
Pharmaceutical Materials 2025-03-02
CAS Number: 20776-51-6
Molecular Formula: C7H6BrNO2
Molecular Weight: 216.032 g/mol
Appearance: White solid
Usage: It is primarily used as an important pharmaceutical intermediate.
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| Attribute | Details |
|---|---|
| Chemical Name | 2-Amino-3-Bromobenzoic Acid |
| Synonyms | 3-Bromo-2-aminobenzoic acid |
| CAS Number | 20776-51-6 |
| Molecular Formula | C7H6BrNO2 |
| Molecular Weight | 215.02 g/mol (or 216.03 g/mol, depending on source) |
| Appearance | White to pale yellow solid |
| Melting Point | 173-178 °C (varies slightly depending on source) |
| Boiling Point | 343.5 °C at 760 mmHg |
| Density | 1.793 g/cm³ or 1.8±0.1 g/cm³ (varies slightly depending on source) |
| Flash Point | 161.5 °C |
| Solubility | Soluble in organic solvents, slightly soluble in water |
| Stability | Stable under normal conditions; incompatible with oxidizing agents and strong bases |
| Uses | Important intermediate in pharmaceutical synthesis; used as an industrial raw material |
| Production Method | Prepared by adding hydrogen peroxide dropwise to 7-bromoindigo, followed by neutralization with sodium hydroxide, adjusting the pH to 4 with hydrochloric acid, and precipitating the product as a white solid |
| Safety Instructions | Handle with caution; avoid contact with skin, eyes, and inhalation of vapors; wear appropriate protective clothing and gloves; store in a cool, dry place away from incompatible substances; refer to the MSDS for detailed safety information |


