2-Amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propanoic acid
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Category：Chemical Intermediates Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS No.: 5162-90-3 | Molecular Weight: 232.24 g/mol
1. Chemical Identification
| Property | Specification |
|---|---|
| IUPAC Name | 2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid |
| Common Name | Rebamipide |
| Molecular Formula | C₁₂H₁₂N₂O₃ |
| CAS No. | 5162-90-3 |
| Therapeutic Class | Gastric Mucosa Protective Agent |
2. Physical & Chemical Properties
| Parameter | Value |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥99% |
| Melting Point | 290°C (dec.) |
| Density | 1.343 g/cm³ |
| Solubility | Slightly soluble in DMSO (<10 mg/mL); practically insoluble in water |
| Storage | 2-8°C in airtight, light-resistant container |
3. Production & Supply
| Parameter | Detail |
|---|---|
| Annual Capacity | 200 metric tons |
| MOQ | 100g |
| Packaging | 100g (amber glass bottle), 1kg (double PE bag), 25kg (fiber drum) |
| Shelf Life | 36 months |
4. Quality Standards
| Test | Specification |
|---|---|
| Purity (HPLC) | ≥99.0% |
| Related Substances | ≤1.0% total |
| Heavy Metals | ≤10 ppm |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
5. Pharmacological Applications
- Mechanism of Action:
- Stimulates prostaglandin E₂ synthesis
- Increases gastric mucin (MUC5AC) production
- Scavenges hydroxyl radicals
- Clinical Indications:
- Gastric ulcer treatment
- Chronic gastritis management
- NSAID-induced gastric injury prevention
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