2-(2-Methyl-5-bromobenzyl)-5-(4-fluorophenyl)thiophene
Pharmaceutical Materials 2025-03-20
CAS.No：1030825-20-7
Appearance:White powder
Molecular Formula:C18H14BrFS
Purity :HPLC≥99.5%
Capacity:20 tons/month
Molecular weight:361.27
Application:Cagliflozin intermediates, pharmaceutical intermediates
| Property | Details |
|---|---|
| Molecular Formula | C18H14BrFS |
| Molecular Weight | 361.27 g/mol |
| Appearance | Off-white to pale yellow crystalline solid or powder |
| Purity | Typically ≥95% (HPLC) |
| Melting Point | Data not widely available; likely in the range of 150-200 °C |
| Boiling Point | Predicted to be high; exact data not available |
| Density | Approximately 1.4-1.5 g/cm³ (Predicted based on structure) |
| Flash Point | Predicted to be above 200 °C |
| Solubility | Soluble in organic solvents such as DMSO, chloroform, and toluene |
| Applications | Organic synthesis, pharmaceutical research, materials science |
| Synthesis Method | Typically involves coupling reactions and functional group manipulations |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; use in a well-ventilated area |
| Storage | Store in a cool, dry place, away from light and moisture |
| Suppliers | Available through custom synthesis from specialized chemical suppliers |
Overview
2-(2-Methyl-5-bromobenzyl)-5-(4-fluorophenyl)thiophene is a complex organic compound with a molecular formula of C18H14BrFS and a molecular weight of 361.27 g/mol. It typically appears as an off-white to pale yellow crystalline solid or powder with a purity of ≥95% as determined by HPLC. The melting point of this compound is not widely available but is likely in the range of 150-200 °C. It is soluble in organic solvents such as DMSO, chloroform, and toluene, making it suitable for various chemical reactions and syntheses.
Applications
This compound finds applications in organic synthesis, particularly in the development of new pharmaceutical compounds and materials. Its unique structure, featuring a thiophene ring substituted with a bromobenzyl and a fluorophenyl group, provides a versatile platform for further chemical modifications.
Synthesis and Safety
The synthesis of 2-(2-Methyl-5-bromobenzyl)-5-(4-fluorophenyl)thiophene typically involves coupling reactions and functional group manipulations, requiring careful control of reaction conditions. When handling this compound, appropriate safety measures should be taken, including the use of protective equipment and working in a well-ventilated area.
Availability
This compound may not be readily available off-the-shelf and may require custom synthesis from specialized chemical suppliers. Researchers interested in this compound should consult with suppliers to obtain detailed synthesis protocols and safety data sheets.
