2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS NO.:142569-70-8
Pharmaceutical Materials 2025-03-02
Catalog ID:825363
CAS NO.:142569-70-8
Purity:95+%
2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol, with the CAS NO. 142569-70-8, is an important intermediate in the pharmaceutical industry, specifically used in the synthesis of Montelukast, a well-known anti-asthmatic drug. This compound exhibits unique structural features, including a chlorinated quinoline moiety linked to a styrylphenyl group via an ethenyl bridge, further attached to a hydroxypropyl and a 2-propanol moiety. Its complex structure contributes to its specific biological and chemical properties.
| Property | Value |
|---|---|
| CAS NO. | 142569-70-8 |
| Molecular Formula | C29H28ClNO2 |
| Molecular Weight | 457.9911 g/mol |
| Density | 1.245 g/cm³ (approx.) |
| Melting Point | 118-121°C, 60-68°C (reported range) |
| Boiling Point | 636.813°C, 648.9±55.0°C (approx.) |
| Flash Point | 338.932°C, 346.2±31.5°C (approx.) |
| Refractive Index | 1.686, 1.680 (approx.) |
| Vapor Pressure | 0 mmHg at 25°C |
| Appearance | Pale yellow to light yellow powder/foam |
| Solubility | Slightly in chloroform, sparingly in DMSO and methanol |
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