Pharmaceutical Materials

nature:

-Appearance: White crystalline solid

-Solubility: soluble in water and organic solvents such as ethanol and chloroform

Purpose:

1H imidazole, 5,5 ‘- [1,1’ – biphenyl] -4,4 ‘- bis [2- (2S) -2-pyrrolidine hydrochloride (1:4) is mainly used as a catalyst in organic synthesis reactions. It can be used to catalyze the oxidation of alcohol compounds, Grignard reactions of alkynes, esterification reactions of esters, etc.

Manufacturing method:

The synthesis of 1H imidazole, 5,5 ‘- [1,1’ – biphenyl] -4,4 ‘- bis [2- (2S) -2-pyrrolidine hydrochloride (1:4) can be obtained by reacting 1H imidazole with 5,5’ – [1,1 ‘- biphenyl] -4,4’ – diketone hydrochloride under appropriate conditions. This reaction requires the presence of organic solvents and often uses hydrochloric acid as a catalyst.

Security information:

Safety information for 1H imidazole, 5,5 ‘- [1,1’ – biphenyl] -4,4 ‘- bis [2- (2S) -2-pyrrolidine hydrochloride (1:4): Currently available information is limited, and appropriate laboratory safety procedures need to be followed when using, such as wearing personal protective equipment, avoiding contact with skin and eyes, staying away from sources of fire and high temperatures. When using or disposing of this compound, relevant dosage, toxicity, and hazardous substance handling guidelines should be followed, and safety data should be obtained from reliable sources.

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