1,7-Dihydroxynaphthalene CAS：575-38-2
Pharmaceutical Materials 2025-03-02
CAS Number: 575-38-2
Molecular Formula: C10H8O2
Molecular Weight: 160.17
Appearance: White to gray to brown powder or crystal
Melting Point: 175-182°C
Usage: Widely used in the synthesis of dyes and pharmaceutical intermediates.
| Aspect | Details |
|---|---|
| Name | 1.7-Dihydroxynaphthalene |
| Synonyms | 1.7-Naphthalenediol; Naphthalene-1.7-diol; 1.7-Dihydroxynaphthalene |
| CAS Number | 573-58-0 |
| Chemical Formula | C₁₀H₈O₂ |
| Molecular Weight | 160.17 g/mol |
| Physical Properties | – Appearance: Light yellow to beige crystalline solid |
| – Melting Point: 220–222°C | |
| – Solubility: Slightly soluble in water; soluble in organic solvents (e.g., ethanol, acetone) | |
| Synthetic Applications | – Dye Precursor: Essential intermediate in the synthesis of azo dyes, disperse dyes, and vat dyes |
| – Pharmaceuticals: Used in the production of anti-inflammatory and anticancer agents | |
| – Polymer Chemistry: Employed as a monomer in the development of conductive polymers | |
| Biological Activity | – Toxicity: Generally considered non-toxic; LD₅₀ (oral, rat) > 5.000 mg/kg |
| – Antioxidant Properties: Demonstrates radical-scavenging activity in vitro | |
| Industrial Production | – Process: Alkaline fusion of 1.7-naphthalenedisulfonic acid followed by acidification |
| – Optimization: High yields achieved using potassium hydroxide as a fusion agent | |
| Storage Conditions | – Environment: Store in tightly sealed containers away from light and moisture |
| – Stability: Prone to oxidation upon prolonged exposure to air |
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