16-beta Methyl Epoxide
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80021304
CAS NO.981-34-0
Purity 98%
MDL NumberMFCD09038712
EINEC213-563-4
Molecular formula C22H28O5
Molecular weight 372.46
Melting point: 210~220°C
| Category | Information |
|---|---|
| Chemical Properties | 16-beta Methyl Epoxide (also known as DB11) is a steroid derivative with the molecular formula C₂₂H₂₈O₅ and a molecular weight of 372.5 g/mol. It is a crystalline compound with a melting point of 210-220°C. |
| Physical Properties | The compound has a predicted boiling point of 564.9±50.0°C and a density of 1.3±0.1 g/cm³. It appears as a white to light beige solid. |
| Solubility | It is slightly soluble in chloroform, dioxane, and DMSO when heated. |
| Applications | 16-beta Methyl Epoxide is a key intermediate in the synthesis of corticosteroid drugs such as betamethasone and dexamethasone. It is used in the production of various pharmaceuticals through modifications at positions 3, 6, 16, and 21. |
| Synthesis | It can be synthesized from Hecogenin through a series of reactions including acetylation, elimination, reduction, ring opening, epoxidation, and other steps. |
| Storage Conditions | It should be stored in a refrigerator to maintain stability. |
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