Active Pharmaceutical Ingredients

Catalog ID80021304

CAS NO.981-34-0

Purity 98%

MDL NumberMFCD09038712

EINEC213-563-4

Molecular formula C22H28O5

Molecular weight 372.46

Melting point: 210~220°C

Category	Information
Chemical Properties	16-beta Methyl Epoxide (also known as DB11) is a steroid derivative with the molecular formula C₂₂H₂₈O₅ and a molecular weight of 372.5 g/mol. It is a crystalline compound with a melting point of 210-220°C.
Physical Properties	The compound has a predicted boiling point of 564.9±50.0°C and a density of 1.3±0.1 g/cm³. It appears as a white to light beige solid.
Solubility	It is slightly soluble in chloroform, dioxane, and DMSO when heated.
Applications	16-beta Methyl Epoxide is a key intermediate in the synthesis of corticosteroid drugs such as betamethasone and dexamethasone. It is used in the production of various pharmaceuticals through modifications at positions 3, 6, 16, and 21.
Synthesis	It can be synthesized from Hecogenin through a series of reactions including acetylation, elimination, reduction, ring opening, epoxidation, and other steps.
Storage Conditions	It should be stored in a refrigerator to maintain stability.

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