Pharmaceutical Materials

1,4-Dithiane-2,5-dihydroxy, also known as 2,5-Dihydroxy-1,4-dithiane, is a sulfur-containing heterocyclic compound with the CAS number 40018-26-6. Its molecular formula is C₄H₈O₂S₂, and its molecular weight is 152.24 g/mol. This compound is characterized by a melting point of approximately 130°C (decomposing) and is commonly found as a crystalline powder ranging from white to yellow in color. It is slightly soluble in water (3.9 g/L at 20°C) and soluble in ethanol. Due to its structural properties, it serves as a valuable intermediate in the synthesis of pharmaceuticals, including antivirals like lamivudine, and is also utilized in flavor and fragrance applications. Its handling requires caution as it is classified as a hazardous substance, necessitating proper storage and safety protocols to prevent inhalation, ingestion, or skin contact.

Usage： Used as lamivudine and other pharmaceutical intermediates.

Packaging and Shipping： 25kgs/Drum or as required by buyer.

Storage: Ventilated low temperature drying warehouse;Store separately with food raw materials, oxidants and halogenated hydrocarbons.

Name	p-Dithiane-2,5-diol
Synonyms	NSC 106280 p-Dithiane-2,5-diol 4-DITHIANE-2,5-DIOL 1,4-Dithiane-2,5-dio 1,4-Dithian-2,5-diol 1,4-DITHIANE-2,5-DIOL MERCATOACETALDEHYDE DIMER 2,5-Dihydroxy-1,4-dithiane 2,5-DIHYDROXY-1,4-DITHIANE
CAS	40018-26-6
EINECS	254-751-6
InChI	InChI=1/C4H8O2S2/c5-3-1-7-4(6)2-8-3/h3-6H,1-2H2/t3-,4+
InChIKey	YUIOPHXTILULQC-UHFFFAOYSA-N

Molecular Formula	C4H8O2S2
Molar Mass	152.24
Density	1.224 (estimate)
Melting Point	130 °C (dec.) (lit.)
Boling Point	244.73°C (rough estimate)
Flash Point	175.5°C
JECFA Number	550
Water Solubility	3.9 g/L (20 ºC)
Solubility	H2O: 0.39% at20°C
Vapor Presure	0Pa at 25℃
Appearance	White to yellowish crystals
Color	White to yellow
BRN	104402
pKa	12.04±0.40(Predicted)
PH	4.9 (3.9g/l, H2O)
Storage Condition	2-8°C
Sensitive	Sensitive to light and humidity
Refractive Index	1.5200 (estimate)
MDL	MFCD00006659
Physical and Chemical Properties	Melting point 130-145°C (dec.) water-soluble 3.9g/L (20°C)
Use	Used as lamivudine and other pharmaceutical intermediates

Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.