Pharmaceutical Materials

1,4-Butenediol, also known as 2-Butene-1,4-diol, is a versatile organic compound with the molecular formula C₄H₈O₂ and a molecular weight of 88.11 g/mol. It exists as a mixture of cis and trans isomers and is widely used as an intermediate in pharmaceuticals, agrochemicals, and polymers. As a key precursor to vitamin B6, pesticides (e.g., endosulfan), and polyester fibers, 1,4-butenediol plays a critical role in synthetic chemistry. Physically, it is a colorless to pale yellow liquid, soluble in water, ethanol, and acetone but insoluble in nonpolar solvents like benzene. Its reactivity stems from the presence of both an alkene and diol functional groups, enabling reactions such as hydration, oxidation, and polymerization. However, its low flash point (128 °C) and toxicity (LD₅₀ in rats: 1.25 mL/kg) necessitate careful handling and storage under inert conditions to prevent decomposition or hazardous reactions.

Usage： Used as an intermediate for the preparation of pesticides, agricultural chemicals and vitamin B6, and a small amount is used in polymer production.

Packaging and Shipping： 200KG/drum or as per buyer requirement.

Storage： Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.

Molecular Formula	C4H8O2
Molar Mass	88.11
Density	1.07 g/mL at 25 °C(lit.)
Melting Point	4-10°C(lit.)
Boling Point	235°C(lit.)
Flash Point	>230°F
Water Solubility	131.4 at 12 mm Hg
Vapor Presure	2.46E-07mmHg at 25°C
Color	yellow
pKa	14.17±0.10(Predicted)
Refractive Index	n20/D 1.479
Physical and Chemical Properties	Character: colorless liquid. boiling point 84 ℃ relative density 1.070 refractive index 1.4770 flash point 128 ℃ soluble in water, ethanol, acetone, almost insoluble in lower aliphatic hydrocarbons or aromatic hydrocarbons.
Use	It can be used as plasticizer of alkyd resin, crosslinking agent of synthetic resin, bactericide, etc. It can also be used for making nylon, Medicine, 1, 4-butanediol, etc

Names and Identifiers

Name	2-Butene-1,4-diol
Synonyms	Butenediol agrisynthb2d butene-1,4-diol 2-Butene-1,4-diol but-2-ene-1,4-diol 1,4-buenedilo(liquid) 1,4-Dihydroxy-2-butene (2E)-2-Butene-1,4-diol (Z)-but-2-ene-1,4-diol (2Z)-but-2-ene-1,4-diol (E)-but-2-ene-1,4-diol (2E)-but-2-ene-1,4-diol CIS-1,4-DIHYDROXY-2-BUTENE
CAS	110-64-5
EINECS	203-787-0
InChI	InChI=1/2C4H8O2/c2*5-3-1-2-4-6/h2*1-2,5-6H,3-4H2/b2-1+;2-1-

110-64-5 – Physico-chemical Properties

Molecular Formula	C4H8O2
Molar Mass	88.11
Density	1.07 g/mL at 25 °C(lit.)
Melting Point	4-10°C(lit.)
Boling Point	235°C(lit.)
Flash Point	>230°F
Water Solubility	131.4 at 12 mm Hg
Vapor Presure	2.46E-07mmHg at 25°C
Color	yellow
pKa	14.17±0.10(Predicted)
Refractive Index	n20/D 1.479
Physical and Chemical Properties	Character: colorless liquid. boiling point 84 ℃ relative density 1.070 refractive index 1.4770 flash point 128 ℃ soluble in water, ethanol, acetone, almost insoluble in lower aliphatic hydrocarbons or aromatic hydrocarbons.
Use	It can be used as plasticizer of alkyd resin, crosslinking agent of synthetic resin, bactericide, etc. It can also be used for making nylon, Medicine, 1, 4-butanediol, etc

110-64-5 – Risk and Safety

Hazard Symbols	Xn – Harmful
Risk Codes	R22 – Harmful if swallowed R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description	S23 – Do not breathe vapour. S24/25 – Avoid contact with skin and eyes. S36 – Wear suitable protective clothing. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
RTECS	EM4970000
FLUKA BRAND F CODES	23
HS Code	29053990

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