1,2,4,5-Tetramethylbenzene
Chemical Additives 2025-03-18
1,2,4,5-Tetramethylbenzene (Durene)
Chemical Formula: C₁₀H₁₄
Structure: Symmetrical aromatic hydrocarbon with four methyl groups (-CH₃) at the 1, 2, 4, and 5 positions of a benzene ring.
Physical Properties
- Appearance: White crystalline solid.
- Odor: Mild aromatic odor.
- Stability: Highly stable due to symmetrical substitution.
Applications
- Organic Synthesis:
- Intermediate for polymers, resins, and specialty chemicals.
- Industrial Chemistry:
- Production of dyes, pigments, and pharmaceuticals.
- High-Performance Polymers:
- Precursor to pyromellitic dianhydride (PMDA), used in polyimides (e.g., heat-resistant materials).
Safety Considerations ⚠️
- Health Hazards:
- Causes irritation to skin and eyes.
- Flammability: Flammable; keep away from open flames or high temperatures.
- Storage: Store in a cool, dry place to maintain stability.
Summary:
Durene’s symmetrical structure and stability make it vital in polymer chemistry and industrial synthesis. Its role in producing high-performance polyimides underscores its technical importance, while proper handling ensures safety due to its flammability.
1.2.4.5-Tetramethylbenzene (Durene) Technical Overview
1. Fundamental Chemical Properties
| Property | Specification |
|---|---|
| Chemical Name | 1.2.4.5-Tetramethylbenzene |
| Common Name | Durene |
| CAS Number | 95-93-2 |
| Molecular Formula | C₁₀H₁₄ |
| Molecular Weight | 134.22 g/mol |
| Appearance | White crystalline solid |
| Melting Point | 79-81°C |
| Boiling Point | 196-198°C |
| Density (20°C) | 0.838 g/cm³ |
| Solubility | Soluble in organic solvents, insoluble in water |
| Flash Point | 73°C |
2. Industrial Applications and Characteristics
| Application Area | Primary Use |
|---|---|
| Organic Synthesis | Precursor for polyimide resins |
| Specialty Chemicals | Intermediate for dyes and pigments |
| Polymer Industry | Monomer for high-performance polymers |
| Research & Development | Model compound in crystallography studies |
| Fuel Additives | Octane booster component |
| Characteristic | Performance Value |
|---|---|
| Thermal Stability | Excellent (up to 300°C) |
| Chemical Reactivity | Moderate (electrophilic substitution) |
| Purity Requirement | ≥98% for most applications |
| Storage Stability | Stable under inert atmosphere |
3. Safety and Handling Guidelines
| Safety Aspect | Requirement |
|---|---|
| Storage Conditions | Cool, dry place away from oxidizers |
| Personal Protection | Gloves, safety glasses |
| Fire Fighting Measures | Dry chemical, CO₂, foam |
| Environmental Impact | Low water solubility reduces aquatic risk |
| Disposal Method | Incineration or chemical waste facility |
1.2.4.5-Tetramethylbenzene is particularly valued in advanced material synthesis due to its symmetrical molecular structure and thermal stability. The compound requires standard aromatic hydrocarbon handling precautions.


