Pharmaceutical Materials

1,1-Cyclohexanediacetic acid mono amide (CAS No.: 99189-60-3), commonly referred to as CAM, is a versatile intermediate with significant applications in pharmaceutical synthesis. Structurally, it features a cyclohexane ring functionalized with two acetic acid groups and an amide moiety, contributing to its reactivity and solubility properties. This compound is sparingly soluble in water but soluble in organic solvents like DMSO and methanol, facilitating its use in organic reactions. CAM is widely recognized as a key intermediate in the synthesis of gabapentin, an anticonvulsant and neuropathic pain medication. Its role in pharmaceutical chemistry stems from its ability to introduce cyclohexane and acetic acid functionalities into target molecules, enhancing their pharmacological properties. The compound’s stability under ambient conditions and predictable reactivity make it a preferred choice in medicinal chemistry workflows.

Usage：Used as pharmaceutical intermediate.

Packaging and Shipping：25kg/drum or as per buyer’s requirements.

Storage: Storage in ventilated low temperature dry warehouse; Keep container closed and separately from open flame and heat source.

Name	1,1-Cyclohexanediacetic acid mono amide
Synonyms	CAM CALM CAMI CALM1 DD132 CALML2 Calmodulin1, His tagged human 3,3-Pentamethyleneglutaramic acid 1,1-Cychexanediaceticacidmonoamide 1,1-Cyclohexanediacetic acid monoamide 1,1-CYCLOHESANEDIACETIS ACID MONOAMIDE 1,1-cyclohexane diacetic acid monoamide 1,1-Cyclohexanediacetic acid mono amide 1,1-Cyclohexane diacetic acid mono amide [1-(2-amino-2-oxoethyl)cyclohexyl]acetate [1-(2-amino-2-oxoethyl)cyclohexyl]acetic acid
CAS	99189-60-3
EINECS	449-430-4
InChI	InChI=1/C10H17NO3/c11-8(12)6-10(7-9(13)14)4-2-1-3-5-10/h1-7H2,(H2,11,12)(H,13,14)/p-1

Molecular Formula	C10H17NO3
Molar Mass	199.25
Density	1.135±0.06 g/cm3(Predicted)
Melting Point	141-146 °C (lit.)
Boling Point	443.6±18.0 °C(Predicted)
Flash Point	222.1°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	4.14E-09mmHg at 25°C
Appearance	White powder
Color	White to Off-White
pKa	4.72±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD02181086
Physical and Chemical Properties	Melting point 143-146°C

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