1-Pentanone,2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-,(2S)-,2,2,2-trifluoroacetate(1:1)
Pharmaceutical Materials 2025-03-02
Catalog ID:98534
CAS NO.:247068-85-5
Purity:98%
MDL Number:MFCD28100284
Molecular Weight:285.26
| Chemical Name | 1-Pentanone,2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-,(2S)-,2,2,2-trifluoroacetate (1:1) | |
| CAS No. | 247068-85-5 | |
| Molecular Formula | C₉H₁₇NO₂·C₂HF₃O₂ | |
| Molecular Weight | ~285.26 g/mol (calculated) | |
| Chirality | Two stereocenters (S- and R-configurations) | |
| Appearance | Typically white to off-white solid or powder | |
| Solubility | Soluble in polar solvents (e.g., DMSO, methanol); limited solubility in water | |
| Key Functional Groups | Amino group, methyl substituent, epoxy ketone, trifluoroacetate salt | |
| Synthesis | Multistep peptide coupling involving protected amino acids and epoxidation | |
| Applications | Pharmaceutical intermediate for proteasome inhibitors (e.g., carfilzomib), drug discovery, and chemical synthesis. | |
| Safety Information | GHS Hazard Statements: Likely skin irritant (H315), serious eye irritant (H319), and respiratory irritant (H335). Precautions: Follow standard lab safety protocols (gloves, goggles, ventilation). |
,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
