Pharmaceutical Materials

CAS No.108-16-7

Name

1-Dimethylamino-2-propanol

Synonyms

DMIPA

1-Dimethylamino-2-propanol

1-dimethylaminopropan-2-ol

1-(dimethylamino)-2-propano

1-(dimethylamino)butan-2-ol

1.1-dimethylaminopropanol-2

N,N-Dimethylisopropanolamine

1.1-Dimethylaminopropan-2-ol

1-(dimethylamino)propan-2-ol

1.1-(Dimethylamino)propanol-2

Dimethyl(2-hydroxypropyl)amine

1-N,N-Dimethylin-2-propanolamine

2-Propanol, 1.1-(dimethylamino)-

(2S)-1-(dimethylamino)propan-2-ol

(2R)-2-hydroxy-N,N-dimethylpropan-1-aminium

(2S)-2-hydroxy-N,N-dimethylpropan-1-aminium

 

Attribute	Details
Chemical Name	1-Dimethylamino-2-propanol
CAS Number	108-16-7
Synonyms	1-(Dimethylamino)-2-propanol; N,N-Dimethylisopropanolamine; DMIPA; N,N-Dimethyl-iso-propanolamine
Molecular Formula	C5H13NO
Molecular Weight	103.16 g/mol
Chemical Structure	CH3CH(OH)CH2N(CH3)2
Appearance	Colorless to light yellow transparent liquid
Melting Point	-40°C
Boiling Point	121-127°C
Density	0.837 g/mL at 20°C
Refractive Index	1.4183-1.4203
Flash Point	35°C
Solubility	Miscible with water
Uses	Used as an intermediate in the pharmaceutical industry (e.g., in the synthesis of promethazine); as a stabilizer for acrylonitrile polymers; and as a raw material for organic synthesis
Production Methods	Produced by the reaction of propylene oxide with dimethylamine or by the reaction of chloroisopropanol with dimethylamine
Safety Information	Handle with caution; may be harmful if swallowed or inhaled; may cause skin irritation and serious eye damage; avoid contact with skin, eyes, and clothing; wear appropriate personal protective equipment; in case of spill or leak, isolate the area, wear self-contained breathing apparatus, and use dry sand, earth, or inert materials to absorb the spill and prevent spreading; do not use water or other water-based extinguishers as they may cause the material to react violently; store in a cool, dry, well-ventilated area away from heat, sparks, and incompatible materials.

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