Pharmaceutical Materials

1-Bromoadamantane, also known as 1-adamantyl bromide, is a key halogenated derivative of adamantane with the molecular formula C₁₀H₁₅Br and a molecular weight of 215.13 g/mol. It serves as a critical intermediate in pharmaceutical synthesis, particularly in the production of antiviral drugs like amantadine hydrochloride. Recent studies highlight its role in organic chemistry, where it acts as a building block for new materials and pharmaceuticals. Synthesized via bromination of adamantane using bromine and subsequent purification, 1-bromoadamantane exhibits high purity (up to 99%) and melting point stability (116–118 °C). Its solubility in chloroform and insolubility in water make it suitable for solvent-based reactions. However, its sensitivity to moisture and air necessitates storage under inert gas to prevent decomposition.

Usage： Pharmaceutical Intermediates,It is an intermediate in the synthesis of amkanane salt.

Packaging and Shipping： 25KG/drum or as per buyer’s requirements.

Storage: Storage in ventilated low temperature dry warehouse; Keep container closed and separately from open flame and heat source.

Name	1-Bromoadamantane
Synonyms	1-BroMoadaMantan Adamantyl bromide 1-Bromoadamantane 1-bromoadmantance 3-Bromoadamantane 1-Bromoadamamtane 1-Bromo adamantine 1-Adamantyl bromide 11 -BROMOADAMANTANE RARECHEM AQ TC 1019 Adamantane, 1-bromo- LABOTEST-BB LT00239617 1-broMine adaMantanone 1-BROMOADAMANTANE FOR SYNTHESIS 1-bromotricyclo(3.3.1.13,7)decane 1-Bromotricyclo[3.3.1.1(3,7)]decane 1-Bromotricycol[3.3.1.1.(1,7)decane 1-Bromotricyclo[3.3.1.1(3.7)]decane 1-Bromoadamantane,1-Adamantyl bromide
CAS	768-90-1
EINECS	212-200-7
InChI	InChI=1/C10H15Br/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6H2/t7-,8+,9-,10-
InChIKey	VQHPRVYDKRESCL-UHFFFAOYSA-N

Molecular Formula	C10H15Br
Molar Mass	215.13
Density	1.2686 (rough estimate)
Melting Point	116-118 °C (lit.)
Boling Point	248.79°C (rough estimate)
Flash Point	96.4°C
Water Solubility	It is soluble in organic solvents and insoluble in water.
Solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
Vapor Presure	0.0587mmHg at 25°C
Appearance	White to white-like crystals
Color	White to yellow
BRN	1098857
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	1.6411 (estimate)
MDL	MFCD00074721
Physical and Chemical Properties	Melting point 116-118 ° C, soluble in chloroform.
Use	Intermediates in the synthesis of amantadine hydrochloride

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