Pharmaceutical Materials

1-Bromo-2,5-difluorobenzene (CAS No.: 399-94-0), also known as 2,5-difluorobromobenzene, is a vital intermediate in organic synthesis, particularly in pharmaceuticals, agrochemicals, and liquid crystal materials. Its structure features a bromine atom and two fluorine substituents on a benzene ring, imparting unique reactivity and stability. As a fluorinated aromatic compound, it serves as a key building block for the synthesis of fluorinated drugs, enhancing their metabolic stability and bioavailability. Additionally, its application in agrochemicals leverages its lipophilicity and target specificity. The compound is also utilized in liquid crystal formulations due to its molecular alignment properties. With a melting point of -31°C and a boiling point of 58-59°C (20 mmHg), it is a colorless liquid with moderate solubility in organic solvents, facilitating its handling in laboratory and industrial processes.

Usage：Used as pharmaceutical intermediates and organic synthetic intermediates.

Packaging and Shipping： 200L or as per buyer’s requirements.

Storage: Storage in ventilated low temperature dry warehouse; Keep container closed and separately from open flame and heat source.

Name	1-Bromo-2,5-difluorobenzene
Synonyms	399-94-0 1-Bromo-2,5-difluoro 2,5-DIFLUOROBROMOBENZENE 1,4-Difluoro-2-bromobenzene 1-BROMO-2,5-DIFLUOROBENZENE 2-BROMO-1,4-DIFLUOROBENZENE 1-Bromo-2,5-difluorobenzene (1R,2R)-2-phenylcyclopropanecarboxylic acid
CAS	399-94-0
EINECS	206-920-0
InChI	InChI=1/C10H10O2/c11-10(12)9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6H2,(H,11,12)/t8-,9+/m0/s1
InChIKey	XCRCSPKQEDMVBO-UHFFFAOYSA-N

Molecular Formula	C6H3BrF2
Molar Mass	192.99
Density	1.708g/mLat 25°C(lit.)
Melting Point	−31°C(lit.)
Boling Point	58-59°C20mm Hg(lit.)
Flash Point	149°F
Water Solubility	Insoluble
Vapor Presure	0.000165mmHg at 25°C
Appearance	clear liquid
Specific Gravity	1.708
Color	Colorless to Light yellow to Light orange
BRN	1680893
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	n20/D 1.508(lit.)
Physical and Chemical Properties	Density 1.708 melting point -31°C boiling point 58-59 ° C (20 mmHg) refractive index 1.5075-1.5095 flash point 65°C water-soluble INSOLUBLE
Use	Used as pharmaceutical, pesticide, liquid crystal material intermediates

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