1-Acetyl-2-phenylhydrazine
Pharmaceutical Materials 2025-03-02
CAS Number: 114-83-0
Molecular Formula: C8H10N2O
Molecular Weight: 150.18 g/mol
Appearance: Colorless needle-like crystals or white solid
Melting Point: 128-132°C
Usage: Used in organic synthesis, pharmaceuticals, and as an intermediate.
| Attribute | Details |
|---|---|
| Chemical Name | 1-Acetyl-2-phenylhydrazine |
| Synonyms | N-Acetyl-N-phenylhydrazine; 1-Acetyl-2-phenylhydrazine; N-Acetylphenylhydrazine; Acetylphenylhydrazine; β-Acetylphenylhydrazine |
| CAS Number | 114-83-0 |
| Molecular Formula | C8H10N2O |
| Molecular Weight | 150.18 g/mol |
| Appearance | White or pale yellow solid, sometimes described as a colorless prism or powder |
| Melting Point | 116-118°C |
| Solubility | Soluble in hot water and ethanol; slightly soluble in cold water and ether |
| Chemical Properties | 1-Acetyl-2-phenylhydrazine is an organic compound belonging to the hydrazine family. It is a white or pale yellow solid with a specific melting point. It reacts with oxyhaemoglobin to form free radicals and can be used to induce haemolytic anaemia for studies of the hematopoietic system. |
| Applications | Used as an organic synthesis intermediate and a stabilizer. It is also used in the preparation of chlornidazine, a drug with antitumor activity. Additionally, it serves as a vascular tumor inducer in experimental animal models. |
| Safety Information | May be harmful if swallowed or inhaled. Causes eye, skin, and respiratory irritation. May cause damage to the red blood cells, leading to haemolytic anaemia. Handle with caution and avoid contact with skin, eyes, and clothing. Store in a cool, dry place away from incompatible materials and oxidizing agents. |
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