1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
Category：Pharmaceutical Materials
Introduction
1-(4-methoxyphenyl) -7-oxo-6-[4-(2-oxopiperidine-1-yl) phenyl]-4,5,6, 7-tetrahydro-1H-pyrazolo [3,4-C] Pyridine-3-carboxylic acid ethyl ester is an intermediate for the preparation of apixaban. apixaban is an antithrombotic drug. It is a direct inhibitor of factor Xa jointly developed by Bristol-Myers Squibb and Pfizer. It was approved for listing in the European Union in March 2011, and F DA approved the drug for listing in the United States in December 2012. Name: 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester CAS: 503614-91-3 Appearance: White powder Assay: ≥99% Capacity: 50mt/year Min.Package: 100gram Application: Apixaban intermediate Standard: Enterprise export
Molecular Formula: C27H28N4O5 Molecular Weight: 488.54 CAS Registry Number: 503614-91-3
| Name | 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester |
| Synonyms | Ethyl 1-(4-methoxyphenyl) -7-oxo-6-(4-(2-oxopiperidin-1-yl) -4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazo ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate 1H-Pyrazolo[3,4-c]pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-,ethylester 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 4,5,6,7-Tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1h-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, ethyl ester |
| CAS | 503614-91-3 |
| EINECS | 700-890-7 |
| Molecular Formula | C27H28N4O5 |
| Molar Mass | 488.54 |
| Density | 1.34 |
| Melting Point | 175 – 180°C |
| Boling Point | 758.7±60.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.001Pa at 25℃ |
| Appearance | Solid |
| Color | White to Pale Beige |
| pKa | 0.78±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Use | This product is for scientific research only and shall not be used for other purposes. |
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