1-(2-Tetrahydropyranyl)-1H-pyrazole-5-boronic acid pinacol ester
Pharmaceutical Materials 2025-03-20
CAS.No：903550-26-5
Molecular Formula: C14H23BN2O3
Application: Pharmaceutical intermediates
| Property | Details |
|---|---|
| Molecular Formula | C14H23BN2O3 |
| Molecular Weight | 278.16 g/mol |
| CAS Number | N/A (specific CAS may vary based on synthesis route) |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥95% |
| Melting Point | Predicted to be in the range of 150-160 °C (specific value may vary) |
| Boiling Point | Predicted to be above 300 °C at 760 mmHg |
| Density | Predicted to be around 1.1-1.2 g/cm³ |
| Solubility | Soluble in organic solvents such as THF, DMF, and DMSO; slightly soluble in water |
| Applications | Organic synthesis, pharmaceuticals, and materials science |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from moisture and strong acids |
| Suppliers | Available from specialized chemical suppliers globally |
Applications
1-(2-Tetrahydropyranyl)-1H-pyrazole-5-boronic Acid Pinacol Ester is a specialized compound used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its unique structure, featuring a pyrazole ring, a tetrahydropyranyl group, and a boronic acid pinacol ester, provides versatile reactivity and makes it a valuable intermediate in the synthesis of complex molecules.
In pharmaceuticals, this compound can be utilized in the development of drugs with enhanced biological activity and specificity. The pyrazole ring and tetrahydropyranyl group can be functionalized to introduce diverse chemical groups, modulating the pharmacological activity of drug molecules.
In materials science, 1-(2-Tetrahydropyranyl)-1H-pyrazole-5-boronic Acid Pinacol Ester serves as a building block for the synthesis of polymers and materials with tailored properties. Its boronic acid pinacol ester group can be used in various coupling reactions to create new materials with improved performance characteristics.
Its solubility in organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
