1-(2-Hydroxyethyl)piperazine CAS No.103-76-4
Pharmaceutical Materials 2025-03-20
CAS No.103-76-4
Name
N-(2-Hydroxyethyl)piperazine
Synonyms
NSC 38969
NSC 26884
NSC 60706
1-Piperazineethanol
N-(2-Hydroxyethyl)pi
Piperazineethanol, 1-
Hydroxyethyl piperazine
2-piperazin-1-ylethanol
2-(1-Piperazino)ethanol
1-piperazin-1-ylethanol
1-(2-Hydroxyethyl)piperazine
N-(2-Hydroxyethyl)piperazine
N-(2-Hydroxyethyl) piperazine
1-(2-hydroxyethyl)piperazinediium
(2E)-3-(naphthalen-2-yl)prop-2-enoic acid
2-(Piperazin-1-yl)ethan-1-ol, 1-Hydroxy-2-(piperazin-1-yl)ethane
1-(2-Hydroxyethyl)piperazine,2-Piperazinoethanol, Piperazine-1-ethanol
| Attribute | Description |
|---|---|
| Chemical Name | 1-(2-Hydroxyethyl)piperazine |
| CAS Number | 103-76-4 |
| Formula | C6H14N2O |
| Molecular Weight | 130.19 g/mol |
| Synonyms | 2-(1-Piperazinyl)ethanol; 1-(2-Hydroxy-ethyl)-piperazine; 1-(2-Ethanol)piperazine; 1-(β-Hydroxyethyl)piperazine; 2-Piperazinoethanol |
| Appearance | Colorless to slightly yellow liquid |
| Odor | Slightly amine-like |
| Density | Approx. 1.05 g/mL at 25°C |
| Boiling Point | 212-214°C (760 mmHg) |
| Flash Point | >110°C (closed cup) |
| Refractive Index | 1.488-1.492 (20°C) |
| Solubility | Miscible with water, ethanol, and many organic solvents |
| pH (1% aqueous solution) | Approx. 8-10 (may vary slightly depending on purity and preparation) |
| Uses | – Used as an intermediate in the synthesis of pharmaceuticals, surfactants, and polymers. – As a corrosion inhibitor and scale inhibitor in water treatment. – In the formulation of cosmetics and personal care products due to its humectant and emulsifying properties. – As a catalyst in various chemical reactions. |
| Safety Information | – May cause skin and eye irritation. – Ingestion may be harmful. – Avoid contact with oxidizing agents. – Store in a cool, dry place, away from direct sunlight and sources of ignition. |
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