1-Naphthaleneboronic acid

13922-41-3 – Names and Identifiers Name 1-Naphthylboronic acid Synonyms RARECHEM AH PB 0125 1-Naphthylbenzoic acid 1-Naphthylboronic acid (1-Naphthyl)boranediol 1-Naphthylboranic acid (1...

Introduction

13922-41-3 – Names and Identifiers

Name 1-Naphthylboronic acid
Synonyms RARECHEM AH PB 0125
1-Naphthylbenzoic acid
1-Naphthylboronic acid
(1-Naphthyl)boranediol
1-Naphthylboranic acid
(1-Naphthyl)boranic acid
ALPHA-NAPHTHYLBORIC ACID
1-Naphthaleneboronic acid
Naphthalene-1-boronic acid
naphthalen-1-ylboronic acid
Naphthalenyl-1-boronic acid
(1-Naphthyl)dihydroxyborane
1-(Dihydroxyboryl)naphthalene
naphthalen-1-yl-1-boronic acid
1-Naphthaleneboronic Acid (contains varying amounts of Anhydride)
CAS 13922-41-3
EINECS 604-119-4
InChI InChI=1/C10H9BO2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7,12-13H
InChIKey HUMMCEUVDBVXTQ-UHFFFAOYSA-N

13922-41-3 – Physico-chemical Properties

Molecular Formula C10H9BO2
Molar Mass 171.99
Density 1.21±0.1 g/cm3(Predicted)
Melting Point 208-214°C(lit.)
Boling Point 381.9±25.0 °C(Predicted)
Flash Point 184.8°C
Water Solubility 2.5 g/100 mL
Vapor Presure 1.63E-06mmHg at 25°C
Appearance White-like to pink powder
Color Off-white to pink beige
BRN 2937504
pKa 8.53±0.30(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index 1.638
MDL MFCD00019722
Physical and Chemical Properties Melting point 210-211°C
water-soluble 2.5g/100 mL
Use Used as a drug Intermediate

13922-41-3 – Risk and Safety

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
S37/39 – Wear suitable gloves and eye/face protection
WGK Germany 3
HS Code 29319090
Hazard Class IRRITANT

13922-41-3 – Reference Information

Uses 1-naphthalene boronic acid is a useful synthetic intermediate. It is a reagent for the synthesis of potassium aryl trifluoroborate, which is the precursor of aryl difluoroborate Lewis acid. It can also be used to prepare high-yield bicyclic compounds by Suzuki coupling.
Used as a pharmaceutical intermediate

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