mPEG-NH2 CAS NO.: 80506-64-5
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Category：Biomedicine MOQ:100KG Shipped directly from China
Introduction
CAS NO.: 80506-64-5
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
mPEG-NH2: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | mPEG-NH2 (Methoxy Polyethylene Glycol-Amine) |
| CAS Number | 80506-64-5 |
| Molecular Formula | CH₃O(CH₂CH₂O)ₙCH₂CH₂NH₂ (where n varies based on PEG chain length) |
| Molecular Weight | Common molecular weights: 350, 500, 550, 750, 1k, 2k, 3.4k, 5k, 10k, 20k |
| Appearance | White to off-white solid or viscous liquid, depending on molecular weight |
| Solubility | Soluble in water and most organic solvents (e.g., DMSO, DMF, DCM, ethanol) |
| Storage Conditions | Store at -20°C, keep dry and avoid light |
| Purity | ≥95% |
mPEG-NH2: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | Methoxy PEG Amine, mPEG-Amine, MPEG-NH2 |
| Structure | Consists of a methoxy polyethylene glycol (mPEG) chain and a terminal amine (NH₂) group |
| Applications | – Bioconjugation: Used to modify proteins, peptides, and other biomolecules by forming stable amide bonds with carboxyl groups.<br>- Drug Delivery: Enhances solubility and stability of therapeutic agents.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – Amine Group: Reacts with carboxylic acids, NHS esters, and other amine-reactive groups.<br>- PEG Chain: Provides hydrophilicity and reduces protein adsorption. |
| Packaging and Price | – Available in various molecular weights and packaging sizes (e.g., 100mg, 250mg, 500mg, 1g, 5g).<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use. |
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