Benfotiamine CAS 22457-89-2
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Category：Vitamins MOQ:100KG Shipped directly from China
Introduction
Benfotiamine is a fat soluble vitamin B1 derivative. After intake of Benfotiamine, the maximum plasma concentration of vitamin B1 is about 5 times higher than that of vitamin B1, and the maximum bioavailability is about 3.6 times higher than that of vitamin B1, and it is higher than other fat soluble vitamin B1 derivatives. Human and animal studies have shown that the bioavailability and biological activity of Benfotiamine are higher than those of water-soluble vitamin forms.
Product name:
Benfotiamine
Molecular Formula:
C19H23N4O6PS
Molecular Weight:
466.448
CAS No.:
22457-89-2
Description
Benfotiamine is pale-yellow or almost white powder; odorless. It is insoluble in water, methanol, ethanol, ether and chloroform, soluble in sodium hydroxide and sodium carbonate solution, slightly soluble in dilute hydrochloric acid solution.
Application
(1) Used for the prevention and treatment of vitamin B1 deficiency;
(2)Used for replenishment when the demand for vitamin B1 is increased and the intake is insufficient from food;
(3) Used for the treatment of non-alcoholic Wernicke encephalopathy;
(4) Used for the treatment of beriberi;
(5) Used for the treatment of the following diseases, it is presumed to be associated with vitamin B1 deficiency and metabolic disorders, such as: neuralgia; muscle pain, joint pain; peripheral neuritis, peripheral nerve palsy; myocardial metabolic disorder; constipation and other gastrointestinal motility obstacle.
| Parameter | Specification |
|---|---|
| Chemical Name | S-Benzoylthiamine O-monophosphate. |
| CAS Number | 22457-89-2. |
| Molecular Formula | C₁₉H₂₂NO₄PS. |
| Molecular Weight | 391.42 g/mol. |
| Appearance | White to off-white crystalline powder. |
| Purity (HPLC) | ≥98.0% (dry basis). |
| Melting Point | 138–142°C. |
| Solubility | Freely soluble in methanol/ethanol; slightly soluble in water. |
| Water Content | ≤1.0% (Karl Fischer). |
| Heavy Metals | Pb ≤2 ppm; As ≤1 ppm; Hg ≤0.1 ppm; Cd ≤0.5 ppm (AAS/ICP-MS). |
| Assay Method | UV spectrophotometry (λ=364 nm) or HPLC. |
| Packaging | Aluminum foil bags with desiccant; available in 1kg, 5kg, or 25kg drums. |
| Storage | Cool (<25°C), dry, light-protected; shelf life 24 months when sealed. |
| Certifications | USP/NF compliant; Kosher/Halal available upon request. |
| Applications | Pharmaceutical API, dietary supplements (enhanced bioavailability of thiamine). |
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