Tetracaine HCl CAS NO.136-47-0
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017135
CAS NO.136-47-0
Purity 98%
MDL NumberMFCD00038912
EINEC205-248-5
Molecular formula C15H24N2O2.HCl
Molecular weight 300.8242
Melting point: 130~145°C
| Aspect | Details |
|---|---|
| Mechanism of Action | Tetracaine HCl blocks sodium ion channels required for the initiation and conduction of neuronal impulses, thereby providing local anesthesia. |
| Clinical Uses | It is used as a rapid and short-acting topical ophthalmic anesthetic for procedures requiring temporary numbing of the eye. |
| Dosage Forms | Available as a 0.5% ophthalmic solution for topical use in the eye. |
| Storage Conditions | Store at 15° to 25°C (59° to 77°F) and protect from light. Do not use if the solution contains crystals, is cloudy, or discolored. |
| Special Precautions | – Do not use intracamerally as it may damage corneal endothelial cells.<br>- Prolonged use or abuse may lead to corneal epithelial toxicity and permanent corneal damage.<br>- Patients should avoid touching the eye for at least 10–20 minutes after application to prevent accidental injuries due to insensitivity.<br>- For administration by healthcare providers only. |
| Side Effects | Transient stinging, burning, conjunctival redness, eye irritation, eye pain, and ocular discomfort. |
| Contraindications | Should not be used in patients with a history of hypersensitivity to any component of the preparation. |
| Toxicity | Overdose or prolonged use may lead to corneal opacification, ulceration, and visual loss. |
| Monitoring | Continuous ECG and pulse oximetry, intermittent blood pressure monitoring, and inspection of respiratory rate are recommended during administration. |
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