Oxygen-fluorine acid
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Category：Pharmaceutical Materials Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS Number: 82419-35-0
Chemical Formula: C13H9F2NO4
Molecular Weight: 281.215
Appearance: Colorless gas/grey-yellow powder
Usage: As a fluorinating agent in organic synthesis.
Hazard: Highly reactive, explosive under certain conditions.
| Aspect | Details |
|---|---|
| Name | Oxygen-fluorine acid (Fluoroquinoline Carboxylic Acid) |
| Synonyms | 9.10-Difluoro-2.3-dihydro-3-methyl-7-oxo-7H-pyrido[1.2.3-de]-1.4-benzoxazine-6-carboxylic acid; Oxyfluorine Acid; Fluoroquinolone Intermediate |
| CAS Number | 82419-35-0 |
| Chemical Formula | C₁₃H₉F₂NO₄ |
| Molecular Weight | 281.21 g/mol |
| Physical Properties | – Appearance: Grey-yellow powder |
| – Melting Point: 320–322°C | |
| – Boiling Point: 459.2 ± 45.0°C (760 mmHg) | |
| – Density: 1.6 ± 0.1 g/cm³ | |
| Stability | Stable under recommended storage conditions; avoid moisture and heat |
| Synthetic Route | Hydrolysis of fluoroquinoline carboxylic acid esters in the presence of organic bases |
| Applications | – Pharmaceuticals: Key intermediate for fluoroquinolone antibiotics (e.g., ofloxacin) |
| – Research: Synthesis of novel fluoroquinolone derivatives | |
| Safety Precautions | – Handling: Use PPE; avoid inhalation, skin, or eye contact |
| – Storage: Keep in airtight containers in a cool, dry place | |
| MSDS Highlights | – GHS Classification: Skin/eye irritant (Category 2); respiratory irritant |
| – First Aid: Rinse affected areas with water; seek medical attention if symptoms persist |
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