
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
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Category:Active Pharmaceutical Ingredients Own Brand:MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID95317
CAS NO.686770-61-6
Purity 98%
MDL NumberMFCD04457599
EINEC Molecular Formula C22H18N4O2S3
Molecular Weight 466.599
| Category | Content |
|---|---|
| Generic Name | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Chemical Formula | C24H20N4O3S2 |
| CAS Number | 1082065-99-3 |
| Molecular Weight | 484.57 g/mol |
| Physical Properties | – Appearance: White or off-white crystalline powder.<br>- Solubility: Soluble in ethanol and dimethylformamide, slightly soluble in ether, almost insoluble in water. |
| Mechanism of Action | This compound is a derivative of nepafenac, a nonsteroidal anti-inflammatory drug (NSAID) that acts as a prodrug. It is rapidly converted to its active metabolite, amfenac, which inhibits cyclooxygenase (COX) enzymes, reducing inflammation and pain. |
| Applications | – Research use as an intermediate or analog of nepafenac.<br>- Potential therapeutic applications in ophthalmology for reducing postoperative inflammation and pain. |
| Safety Profile | – Acute toxicity: Oral (Category 5).<br>- Eye irritation: Category 2B.<br>- Aquatic toxicity: Very toxic to aquatic life.<br>- Store at room temperature, protect from moisture and light. |
| Synonyms | – Nepafenac analog<br>- 2-Amino-3-benzoyl-benzeneacetamide (related compound) |
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