
Glyphosate
Glyphosate (CAS No. 1071-83-6)
1. Basic Information
IUPAC Name: N-(Phosphonomethyl)glycine
Synonyms:
Roundup® (Monsanto trade name)
Glyphosate-isopropylammonium (common salt form)
CAS Number:...
Category:Agrochemicals
Introduction
Glyphosate (CAS No. 1071-83-6)
1. Basic Information
- IUPAC Name: N-(Phosphonomethyl)glycine
- Synonyms:
- Roundup® (Monsanto trade name)
- Glyphosate-isopropylammonium (common salt form)
- CAS Number: 1071-83-6
- Molecular Formula: C₃H₈NO₅P
- Molecular Weight: 169.07 g/mol
- Appearance: White crystalline powder
- Odor: Odorless
2. Physical and Chemical Properties
Property | Value |
---|---|
Melting Point | 184–189°C (decomposition) |
Solubility (25°C) | – Water: 10.5 g/L (pH 2.5) |
– Organic solvents: Insoluble in acetone, ethanol | |
pH (1% solution) | 2.3 (acidic) |
Vapor Pressure | 1.31 × 10⁻⁵ mPa (25°C) |
Log Pow | -3.2 (highly hydrophilic) |
3. Chemical Structure
O ║ HO-P-CH₂-NH-CH₂-COOH | OH
4. Hazards (GHS Classification)
- Acute Toxicity:
- Oral LD₅₀ (rat): >5,000 mg/kg (Category 5)
- Dermal LD₅₀ (rabbit): >2,000 mg/kg
- Environmental:
- Toxic to aquatic plants (H411)
- Not classified for bees (LD₅₀ >100 μg/bee)
- Carcinogenicity:
- IARC Group 2A (probable human carcinogen)
- EPA: “Not likely carcinogenic” (2017)
5. Storage and Handling
- Storage:
- Keep in original containers, away from food/feed
- Store at <30°C, protect from moisture
- Handling:
- Use gloves (nitrile) and dust mask
- Avoid spray drift during application
6. Applications
- Herbicide:
- Non-selective weed control (inhibits EPSP synthase)
- Used in agriculture, forestry, and urban areas
- Crop Desiccation: Pre-harvest treatment for cereals