alpha-Arbutin
Chemical Name: 4-Hydroquinone-α-D-glucopyranoside
Synonyms: Arbutin, α-Arbutin
Molecular Formula: C₁₂H₁₆O₇
Molecular Weight: 272.25 g/mol
CAS No.: 84380-01-8
Purity: ≥99.5% (HPLC)
Product Specific...
Category：Chemical Intermediates
Introduction
Chemical Name: 4-Hydroquinone-α-D-glucopyranoside
Synonyms: Arbutin, α-Arbutin
Molecular Formula: C₁₂H₁₆O₇
Molecular Weight: 272.25 g/mol
CAS No.: 84380-01-8
Purity: ≥99.5% (HPLC)
Product Specifications
| Parameter | Specification |
|---|---|
| Appearance | White crystalline powder |
| Melting Point | 195–196°C |
| Solubility | Water: 50 g/L (20°C) |
| Optical Rotation | [α]²⁰D: -64° to -68° (c=1, H₂O) |
| Heavy Metals | ≤10 ppm (Pb, As, Cd, Hg) |
| Production Capacity | 200 metric tons/year |
| Minimum Order | 100 grams |
Key Properties
- Tyrosinase Inhibition: IC₅₀ ~3.5 μM (superior to β-arbutin)
- Stability: pH 3–7, stable up to 80°C
- Safety: Non-irritating (OECD 439 Skin Irritation Test)
Applications
- Cosmetics:
- Skin whitening agent in creams/serums (replaces hydroquinone)
- Brightening efficacy at 1–5% concentration
- Pharmaceuticals:
- Treatment of hyperpigmentation disorders
- Functional Foods:
- Antioxidant additive in health supplements
Packaging & Storage
| Size | Packaging | Storage Conditions |
|---|---|---|
| 100 g | Glass bottle + desiccant | 2–8°C, dry, inert atmosphere |
| 1 kg | Double foil bag | ≤25°C, avoid light |
| Bulk (>10 kg) | Fiber drum (nitrogen flushed) | Humidity <60% RH |
Safety & Compliance
- GHS Classification: Not classified as hazardous
- Recommended PPE: Basic gloves and goggles
- Certifications:
- COSMOS/Ecocert approved
- China FDA Cosmetic Ingredient Directory
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