3,4,5-Trifluorophenol
Category：Pharmaceutical Materials
Introduction
CAS.No：99627-05-1
Appearance:White powder
Molecular Formula:C6H3F3O
Purity:HPLC≥99.5%
Molecular weight:204.39
Capacity:20 tons/month
Application:Pharmaceutical intermediates
| Property | Details |
|---|---|
| Molecular Formula | C6H3F3O |
| Molecular Weight | 148.08 g/mol |
| CAS Number | 930-98-9 |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥98% |
| Melting Point | 62-65 °C |
| Boiling Point | 168-170 °C (at 760 mmHg) |
| Density | 1.53 g/cm³ |
| Solubility | Soluble in organic solvents such as ethanol, ether, and DMSO; slightly soluble in water |
| Applications | Organic synthesis, pharmaceuticals, agrochemicals, and materials science |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from heat and open flames |
| Suppliers | Available from various chemical suppliers globally |
Applications
3.4.5-Trifluorophenol is a valuable compound in organic synthesis, particularly in the production of fluorinated compounds. Its trifluorinated phenol structure provides unique reactivity and physical properties, making it a useful intermediate in the synthesis of various chemicals.
In pharmaceuticals, 3.4.5-Trifluorophenol is utilized in the development of drugs with enhanced metabolic stability and lipophilicity, contributing to improved bioavailability and efficacy. Its fluorinated nature can modulate the pharmacological activity of drug molecules, leading to more effective therapeutic agents.
In agrochemicals, this compound serves as a building block for the synthesis of herbicides and pesticides, offering improved potency and environmental safety. Additionally, 3.4.5-Trifluorophenol finds applications in materials science, where its fluorinated structure can be exploited to create polymers and materials with tailored properties.
Its solubility in organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
